Job Responsibilities

Project Management (PM)

1. Provide input and support development of the project strategy.
2. Work closely with BD and implement/manage communication with external stakeholders at customer side and internal stakeholders (R&D, CMC, Financial, Supply Chain, etc) to proceed order taking and delivery products to customer smoothly.
3. Manage internal negotiation/communication and make alignment with different departments. Responsible for leading cross-functional project teams to ensure that project deliverables are achieved in time and issues and risks are identified and managed.
4. Effectively manages internal and external project stakeholders while working within a matrixed environment.
5. Prepares routine project status updates via formal and informal channels (monthly reports, project review reports, ad hoc reports).
6. Assists the business planning process including estimating, tracking and managing key project activities to support BD functions in planning and prioritization of BD activities.
7. Accountable for the preparation and maintenance of all project documentation and administration.
8. Where relevant, supports collaboration activities with external partners in the preparation and management of legal agreements and integration of services, technologies and capabilities to ensure delivery of project.
9. Participates in the learning and development of junior Project Management staff and provide mentoring and coaching.

Alliance Management (AM)

1. Serves as a point of contact for current and future strategic partnerships with global partners and ensure that the Alliances strategic goals are achieved and that agreed Alliance-related activities are moving forward as scheduled, in coordination with the internal different teams.
2. Develop a global alliance growth plan to drive revenue growth. Identify and capitalize on external strategic opportunities to achieve the short and long-term business goals.
3. Establish new collaborations and gain broader access to our current partner's resources in collaboration and alignment with the Global BD teams.
4. Scout, identify, evaluate and develop new partner network globally. Manage vendor certification process for certain vendors.
5. Train the partners concerning Yaohai’s capacity and capability. Share with the partners the up-to-date marketing materials in a timely manner. Maintain an accurate understanding of Yaohai’s global BD and service direction.
6. Supervise regular performance of business reviews. Manage company intellectual portfolio and maintain relationships with partners. Monitor and track joint business development activities to determine value of each partnership and appropriately allocate sales and technical resources.
7. Manage the strategic business relationship to ensure sales readiness for the business. Assisting global partners in defining business opportunities and establishing collaboration.
8. Revise and manage sales lead generation system resulting in higher lead volume and quality, and ultimately to improve business productivity.
9. Proactively engage in strategic planning/development and risk assessment in the process of annual action plan and global roadmap and propose revision or additions of these plans from R&D and business development perspectives.
10. Keep the BD and partners informed of the target company’s current business portfolio and R&D strategy for developing effective proposals/strategies.
11. Liaise with global partners and internal stakeholders for clarity and understanding to ensure robust management of the partnerships and provide clarity and problem solving to maintain a fluid and transparent relationship with partners.

The Successful Applicant

1. University degree in life science background, preferably in medical, pharmaceutical or biological sciences.
2. An advanced degree (MSc, PhD) or equivalent in a discipline relevant to Science or Engineering or Drug Research and development (e.g. Biology, Pharmacokinetics, Toxicology, Formulation, etc.), PMP certification, Masters of Business Administration (MBA) is preferred.
3. Fluent English is a must and Functional Chinese is plus. Strong communication skills to manage internal and external stakeholders.
4. Over 2 years of PM, AM, BD/Sales, Marketing or R&D experiences in the biotechnology or pharmaceutical industry (Pharma, Biotech, CRO, and CDMO organization or where relevant a biomedical research organization). Proven track record preferably in business development, project management and alliance management. Good knowledge of the Business Development and Alliance Management processes and best practices, from opportunity sourcing to managing strategic partners.
5. In-depth knowledge in drug research, development and manufacturing processes of pharmaceuticals (CMC, non-clinical, clinical, and regulatory) is preferred.
6. Broad experience as a project manager leading cross-functional project teams in a matrixed, global environment, including those with complex technical, geographic, and/or regulatory elements.
7. Demonstrated experience in leading cross-functional teams and delivering projects to meet business objectives on time, within budget and with quality.
8. Proficient in the use of Project Management processes and tools is a clear Plus.
9. Has experience of drafting/issuing Meeting Summary as an official record of meeting for internal and external stakeholders. Experience of writing Meeting Summary in English is a clear Plus.
10. Has strong passion and intensity to manage projects under tough situation and deliver solid results.

Preferable Personal Traits

1. Entrepreneur with strong ability to use initiative, prioritize, multi-task, and work well under pressure to meet deadlines.
2. Well organized and structured, open and outspoken with demonstrated ability to build trustful relationships. Very strong ability to interact with internal and external stakeholders.
3. Excellent strategic thinking, with strong leadership
4. Demonstrated negotiation and advocacy skills
5. Very clear and systematic thinking that demonstrates strong judgment and problem-solving competencies
6. Excellent ability to lead strategic programs complemented by very good analytical skills
7. Demonstrated ability to lead project delivery
8. Very strong communication skills in multicultural, multi-lingual environments
9. Very strong ability to work effectively as part of a multicultural team
10. Very strong ability to exercise high degree of independence to support program delivery and explore new areas of activities

Job Responsibilities

1. Develop and revise the fermentation process development plan in accordance with the project assignment.
2. Organize the writing and implementation of the process development plan according to the development plan, analyze the development results and summarize the developed processes.
3. Participate in the preparation and upgrading SOPs, URS and validation documents, etc. related to fermentation in the department, as well as equipment validation.
4. Be responsible for the technical capacity enhancement of fermentation technicians and guiding their daily work to ensure its orderliness.
5. Draw up product process protocols and take the charge of interdepartmental process transfers.
6. Complete other tasks assigned by the supervisor.

Related Requirements

1. Master’s degree or above in biology-related fields, doctor preferred; experience of recombinant protein fermentation process development, 3 years for master, 1 year for doctor.
2. Able to read English, consult literature and write articles.
3. Good project management and team management experience is preferred.
4. Good at independent problem-solving and communication, progressive, responsible and cooperative.  

Job Responsibilities

1. Develop and revise the purification process development plan in accordance with the project assignment.
2. Organize the writing and implementation of the process development plan according to the development plan, analyze the development results and summarize the developed processes.
3. Participate in the preparation and upgrading SOPs, URS and validation documents, etc. related to purification in the department, as well as equipment validation.
4. Be responsible for the technical capacity enhancement of purification technicians and guiding their daily work to ensure its orderliness.
5. Draw up product process protocols and take the charge of interdepartmental process transfers.
6. Complete other tasks assigned by the supervisor.

Related Requirements

1. Master’s degree or above in biology-related fields, doctor preferred; experience of recombinant protein purification process development, 3 years for master, 1 year for doctor.
2. Able to read English, consult literature and write articles.
3. Good project management and team management experience is preferred.
4. Good at independent problem-solving and communication, progressive, responsible and cooperative.  

Job Responsibilities

1. Be responsible for the discovery, screening and structural modification of nanobodies.
2. Be responsible for the fermentation and purification process development of nanobodies.
3. Be responsible for the establishment of physicochemical, biochemical and activity analysis methods for nanobodies and the development of quality control standards.
4. Be responsible for the construction of nanobody process platform, and cooperate with other departments such as analysis to jointly establish and optimize a GMP production process platform for mass-producible nanobodies.

Related Requirements

1. Doctor’s degree in biology-related fields.
2. Engage in immunology or antibody development researches, preferably experienced in nanobody related researches.
3. Able to read English, consult literature and write articles.
4. Good at independent problem-solving and communication, progressive, responsible and cooperative.  

Job Responsibilities

1. Be responsible for the structure design, preparation process development, and mRNA-LNP preparation process development for mRNA projects.
2. Be responsible for pilot scale up and compliant production of mRNA projects.
3. Be responsible for the establishment of mRNA and mRNA-LNP analytical methods and the development of quality control standards.
4. Be responsible for the construction of mRNA process platform, and cooperate with other departments such as analysis to jointly establish and optimize a GMP production process platform for mass-producible mRNAs.

Related Requirements

1. Doctor’s degree in biology-related fields.
2. Engage in molecular biology researches, preferably experienced in RNA related researches.
3. Able to read English, consult literature and write articles.
4. Good at independent problem-solving and communication, progressive, responsible and cooperative.  

4. Be responsible for the construction of CircRNA process platform, and cooperate with other departments such as analysis to jointly establish and optimize a GMP production process platform for mass-producible CircRNA.

Related Requirements

1. Doctor’s degree in biology-related fields.
2. Engage in molecular biology researches, preferably experienced in RNA related researches.
3. Able to read English, consult literature and write articles.
4. Good at independent problem-solving and communication, progressive, responsible and cooperative.  

Job Responsibilities

1. Be responsible for the development of lateral chromatographic diagnosis kits, product design and development, performance evaluation, process optimization and other work.
2. Be responsible for the preparation of project materials and technical information related to product registration.
3. Develop new product production processes and related system standards to ensure stable performance and quality of future products.
4. Develop the management procedures of the department to meet the relevant regulatory requirements.
5. Assist and guide the production department in the design realization and pilot scale-up for new kits.
6. Be responsible for the optimization of products, raw material screening and related work.
7. Improve the production process and product quality according to the feedback of sales and production departments.
8. Other related work

Related Requirements

1. Master's degree or above in bioengineering-related fields.
2. Familiar with colloidal gold, immunochromatography related work with the experience of 5 years or above.
3. Love R&D, have certain ability to carry out business independently and have industry foresight.

Job Responsibilities

1. Development, optimization, validation, transfer and quality control of analytical methods.
2. Introduction and implementation of new technologies/instruments.
3. Release testing and stability studies of bulk and finished products.
4. Support studies related to the quality attributes of antibodies, such as structure verification.
5. Collaborate with RA/QA/PM/PD for product quality attribute assessment.
6. Be responsible for project docking, and review the designs, protocols and reports of analytical method development.
7. Be responsible for the coordination related to analysis transfer.

Related Requirements

1. Doctor’s degree; major in biotechnology, analytical chemistry, etc., with at least 3 years of relevant work experience.
2. Expertise and laboratory skills in 1 or more of the following technical areas in physicochemical, biochemical and activity analysis: High-performance liquid chromatography, capillary electrophoresis, capillary isoelectric focusing, chromatography-mass spectrometry, infrared, etc.; gel electrophoresis, enzyme-linked immunosorbent, real-time quantitative PCR, surface plasmon resonance, flow cytometry, etc.; Cell based bioactivity analysis methods
3. Fluent writing in Chinese and English; proficient in using office software.
4. Experience in the field of macromolecule biologics is preferred.

Job Responsibilities

1. Undertake mRNA drug development tasks; be responsible for mRNA drug molecular clone and construction, vector design and optimization, expression validation and other related work; undertake mRNA synthesis work.
2. Participate in the development and execution of study plans using in vitro cell strains, and pharmacology (PK/PD) and toxicology study protocols of preclinical animal models; assist in the analysis and compilation of preclinical pharmacokinetic and toxicokinetic experimental data.
3.Participate in the evaluation of the effectiveness and immune effect of mRNA drugs and other related work.
4. Participate in mRNA drug feasibility studies.
5. Participate in intra- and inter-departmental technical and theoretical discussions regarding experimental results and work progress.
7. Coordinate team and interdepartmental work and direct subordinates to carry out the above related technical work.
8. Complete other tasks assigned by the company.

Related Requirements

1. Doctor’s degree, majoring or experienced in tumor biology, tumor immunity, molecular immunity, cellular immunity, antibody engineering, biomedicine, molecular genetics, cell biology, pharmacokinetics, drug analytics, bioengineering, biotechnology, life science or related fields. Experience working with small animal models with tumors is preferred.
2.Specialized in molecular biology related experiments, such as RT-PCR, Q-PCR, plasmid vector construction, nucleic acid extraction, primer design, nucleic acid and protein electrophoresis experiment, etc. Familiar with cell culture, cell transfection, flow cytometry, immunological analysis, biological analysis, etc.
3. Have a good understanding of the principles and technical routes of mRNA drugs and vaccine preparation.
4. Skilled in literature research and data analysis, as well as drafting experimental/project reports.
5. Conscientious and responsible, with strong learning ability, active thinking, good communication and expression skills, and strong English reading ability; corresponding team management experience is preferred. 
6. Passionate, active, adaptive, responsible and cooperative as an entrepreneur.

Job Responsibilities

1. Study, analyze and report the literature about new macromolecule drugs involving antibodies, nanobodies, ADCs, etc.; carry out mAb screening, interaction studies between antibodies and target proteins at molecular and cellular levels, and comparative studies of antibodies expressed in different host cells.
2. Be responsible for in vitro efficacy evaluation and action mechanism studies on candidate hit molecules.
3. Conduct literature research and summary, independently design the experimental protocols, and solve the problems arising from experiments in a timely manner.
4. Write technical documents for patent application, drug registration, etc.
5. Maintain good communication with internal and external technical teams, analyze and solve problems encountered in project implementation, and ensure the progress and quality of the company's ongoing researches.
6. Guiding and leading the common R&D work of relevant technical staff.
9. Complete other tasks assigned by the supervisor.

Related Requirements

1. Doctor’s degree in cell biology, molecular biology, biochemistry, biology, biotechnology, bioengineering or related fields.
2. Experience in R&D or project management on macromolecule biologics, 5 years for masters and 2 years for doctors.
3. Keep an eye on the dynamics of new drug researches at home and abroad, with a keen insight into hotspots and new targets.
4. Familiar with antibody design, expression and modification optimization; experienced in researches; familiar with the macromolecule new drug development industry. First-line researchers able to effectively manage R&D projects in their departments are preferred.
5. Master and be able to apply relevant knowledge, and be familiar with the drug development process.

Job Responsibilities

1. Be responsible for the development and optimization of the prokaryotic fermentation process and the writing of research protocols and reports, so that the developed fermentation process meets IND declaration requirements.
2. Be responsible for/participate in technology transfer of the Company, and responsible for the writing of fermentation process procedures, transfer protocols and batch production records. Be responsible for on-site audits of CDMO sites, and provide technical supports for project CDMO decisions.
3. Be responsible for/participate in the process characterization and validation protocol for recombinant protein-based projects, and responsible for/participate in the implementation of protocols, so that the process meets the requirements for commercial production.
4. Be responsible for the daily use and maintenance of the Company's fermentation equipment, and the various laboratory affairs.
5. Other work related to this position, general or unexpected.

Related Requirements

1. Doctor’s degree in biology-related fields.
2. At least 5 years of experience in fermentation process development; relevant experience in process characterization studies, technology transfer and process validation.  
3. Experience of being responsible for/participating in the successful IND registration of recombinant protein-based drugs or experience in actual production scale-up is preferred.
4. Proficiency in the use of fermenters and experience in fermentation process development.
5. Strong English literature search and reading skills; able to take the initiative to learn about the latest research trends in fermentation processes and regulations, and share with team members

9. Complete other tasks assigned by the supervisor.

Related Requirements

1. Bachelor’s degree or above, with professional background in biology, pharmaceutics, drug quality, etc.
2. Business development experience in CDMO or biologics industry.
3. Overseas resources (Asia Pacific, Europe, North America)

Job Responsibilities

1. Under the leadership of the General Manager of the Group, develop the subsidiary's business plans, guidelines and policies according to the development of strategies and objectives in order to achieve business goals.
2. Be responsible for the establishment and operation management of CRO/CDO technology service platform of the subsidiary, lead each department to complete the business plan, and analyze and improve business performance. 
3. Be responsible for the formation, development and skills training of a technical service team, and construct and develop an excellent high-quality team.
4. Be responsible for the management of external resources such as government departments, cooperation units and customers, shaping a good corporate image;
5. Participate in business negotiations of important projects; organize service teams to design reasonable and efficient routes for molecular, fermentation, purification and preparation process development and optimization, and develop stable and continuously scaled-up upstream and downstream processes; direct research work.
6. Organize technical researches and optimize the workflow during project implementation.

Related Requirements

1. Doctor’s degree in biology-related fields, with at least 8 years of biopharmaceutical work experience and 5 years of R&D management experience. Work experience in CDMO enterprise is preferred.
2. Having fully presided over the process of biological drug development projects from the establishment to organization and implementation, and to the successful declaration of IND; familiar with drug registration and ICH guidelines.
3. Familiar with E. coli and yeast expression system, good at process development or quality research of protein drugs. Work experience in mRNA or nanobody development is preferred.
4. With excellent leadership, organizational and coordination skills, and a keen insight into the biopharmaceutical market.
5. Under 45 years of age.

Job Responsibilities

1. Be responsible for cell culture work, including protocol and report writing, basic operation of cell recovery, amplification and freezing, operation of bioreactors at all levels (shake flask, ambr, 3L reactor, WAVE, 50L reactor), data analysis and summarization, and process scale-up and technology transfer.
2. Be responsible for the general operation of the laboratory, including the “5S” in the area, material procurement and requisition, instrument use and maintenance, drafting and revision of SOPs and other related documents, etc.
3. Other work such as platform enhancement, platform optimization, personnel coaching and training, etc.
4. Ensure quality compliance (for positions engaged in GxP activities).
5. Ensure the integrity, accuracy, authenticity and validity of experimental data.

Related Requirements

1. Major in bioengineering, chemical engineering, pharmaceuticals, etc., doctor’s degree preferred.
2. 3 years of cell culture experience; fresh doctor graduate is acceptable.
3. Proficient in cell growth, metabolism and expression and biochemistry related knowledge; skilled in DOE experimental design and data analysis; proficient in English reading and writing
4. Keep an awareness of delivery and a sense of risk; able to study independently and analyze and solve problems; appreciate team work and be good at implementation.